Monograph No. 047 / Herbals & Others
Herbals & Others
Asian Ginseng: Benefits, Dosage, and Safety
Asian ginseng (Panax ginseng) is a traditional adaptogenic herb whose root contains ginsenosides; NIH sources say short-term oral use appears safe for most adults but evidence for its promoted uses is largely inconclusive.
Asian ginseng (Panax ginseng) is a traditional adaptogenic herb whose root contains ginsenosides; NIH sources say short-term oral use appears safe for most adults but evidence for its promoted uses is largely inconclusive.
What asian ginseng is
Asian ginseng is the root of Panax ginseng, a plant native to the Far East (Korea, northeastern China, and far-eastern Siberia). It has been used in traditional Chinese medicine as a calming agent and as an adaptogen, meaning it is thought to help the body resist physiological and psychological stress. It is one of several types of ginseng; "red ginseng" and "white ginseng" refer to Asian ginseng prepared in two different ways. It is not the same as American ginseng (Panax quinquefolius) or Siberian ginseng/eleuthero (Eleutherococcus senticosus), which is not a true ginseng. The root contains many substances, of which the ones thought to be most important are called ginsenosides (also called panaxosides). It is a botanical dietary supplement, not an essential nutrient, so no Dietary Reference Intake exists for it.
What it does
- Traditionally used as an adaptogen, thought to help the body resist physiological and psychological stress
- Root supplies ginsenosides (panaxosides), the constituents thought to be biologically most important
- Historically promoted, though not proven, for cognitive function such as attention and reaction time in middle-aged adults
- Historically promoted, though not proven, for fatigue, immune support, and sexual function
- Studied for effects on cardiometabolic factors such as fasting blood glucose and cholesterol, with inconclusive results
Intake and dosing
Asian Ginseng is not an essential nutrient, so no Recommended Dietary Allowance or Tolerable Upper Intake Level has been set. Doses in studies vary widely. Because supplement doses are not standardised, discuss an appropriate amount with a clinician or pharmacist.
Deficiency and who is at risk
None. Asian ginseng is a botanical dietary supplement, not an essential nutrient, so there is no deficiency state and no recommended intake.
Groups more likely to fall short
- Not applicable; no deficiency state exists for a non-essential botanical
Who may need more
- No one requires it nutritionally; it is not an essential nutrient
- Adults who choose to use it as a traditional adaptogen or complementary approach, after discussing with a health care provider
- People considering it for erectile dysfunction or fatigue, though NIH notes evidence is limited and inconclusive
Food sources
Not a food nutrient. The source is the root of the Panax ginseng plant, consumed as dried root, teas, or extracts rather than obtained from a normal diet. It is sometimes added to energy drinks and functional beverages.
Forms and absorption
Sold as the dried root and as tablets, capsules, extracts, powders, and teas, and in creams or other preparations for topical use. "Red ginseng" and "white ginseng" are Asian ginseng prepared in two different ways, with differing ginsenoside profiles. Commercial preparations vary widely in ginsenoside content and some contain little or no detectable active ingredient, so potency is inconsistent between products. Standardization, when present, is typically to a percentage of ginsenosides.
Safety, excess and interactions
According to NIH/NCCIH, short-term oral use (up to 6 months) of Asian ginseng in recommended amounts appears to be safe for most people. Questions have been raised about long-term safety, and some experts recommend against use in infants, children, and women who are pregnant or breastfeeding. There is not enough reliable information to know whether topical use on the skin is safe; it might cause irritation and burning. Because it may lower blood sugar, people with diabetes should consult a health care provider first. It may worsen autoimmune disorders and interfere with blood clotting. Some studies suggest oral use may be unsafe in pregnancy, and a constituent has caused birth defects in animals. Because it may interact with medications, anyone taking any medicine should talk with a health care provider before use. Dietary supplements are not approved by the FDA before sale.
Too much
Insomnia (trouble sleeping) is the most common side effect. Uncommon reported effects include severe rash, liver damage, and severe allergic reactions. Asian ginseng may worsen autoimmune disorders and may interfere with blood clotting. Some evidence suggests it may lower blood sugar levels. Other reported effects across sources include headaches, gastrointestinal upset, and elevated or altered blood pressure. Questions have been raised about long-term safety; some experts suggest limiting use. No Tolerable Upper Intake Level has been established.
Interactions to know
- Diabetes medications (insulin, oral antidiabetes drugs): Asian ginseng may lower blood sugar, so combining could cause blood sugar to drop too low; monitor closely
- Anticoagulant and antiplatelet drugs (for example warfarin, aspirin, NSAIDs): may interfere with blood clotting; case reports describe reduced warfarin effect and altered clotting, increasing bleeding or clotting risk
- Immunosuppressants: ginseng can increase immune system activity and may reduce the effectiveness of drugs that suppress the immune system, such as those used after transplant
- Medications processed by liver enzymes (CYP3A4 and other cytochrome P450 substrates): ginseng may change how quickly the liver breaks down some drugs, altering their effects; reported cases of liver toxicity when combined with imatinib and raltegravir
- Antidepressant MAO inhibitors (for example phenelzine): combining may raise the risk of side effects such as headache, restlessness, and insomnia; ginseng-associated mania has been reported
- Stimulants and caffeine: ginseng may add to nervous-system stimulation, potentially increasing heart rate and blood pressure
- Estrogens: ginseng may have estrogen-like effects and could alter the effects of estrogen therapy
- Other blood-sugar-lowering herbs (for example bitter melon, fenugreek): additive lowering of blood sugar
How status is measured
not routinely measured. There is no clinical lab test for Asian ginseng status because it is not an essential nutrient; ginsenoside levels in products or blood are measured only in research settings.
What the evidence supports
We grade the strength of evidence behind each common reason people take asian ginseng, mirroring how the NIH describes it.
NCCIH: some research shows oral Asian ginseng seems to improve sexual function in people with erectile dysfunction; a Cochrane review of 9 studies (587 participants) suggested ginseng may improve erectile function versus placebo, but trials are small and larger studies are needed.
NCCIH cites a 2023 review of 19 studies (2,413 participants) suggesting Asian ginseng alone may have a small beneficial effect on general fatigue, but not all research agrees and formulas with other ingredients differ from ginseng alone.
NCCIH: a small amount of research suggests possible improvement in abstract thinking, attention, arithmetic skills, and reaction time in middle-aged adults but not young adults; any memory benefit appeared to depend on adding ginkgo.
NCCIH cites a 2022 review of 20 studies (1,295 participants) finding improvement in fasting blood glucose, total cholesterol, and some inflammatory markers, but overall research on blood sugar control in diabetes is inconclusive and conflicting.
NCCIH: a very small amount of preliminary research suggests extract may help reduce the risk of developing flu but not the severity or duration of symptoms.
NCCIH: the majority of research shows Asian ginseng does not improve athletic performance.
NCCIH: there is interest in these uses but not enough reliable information to say whether it might be helpful.
Sources
- S1.gov verifiedNIH National Center for Complementary and Integrative Health (NCCIH)Asian Ginseng: Usefulness and Safetywww.nccih.nih.gov/health/asian-ginseng
- S2.gov verifiedNIH Office of Dietary Supplements (ODS)Dietary Supplements: What You Need To Know (ODS directs the public to NCCIH botanical fact sheets; ODS has no dedicated Asian ginseng fact sheet and no DRI exists for this botanical)ods.od.nih.gov/factsheets/list-all/
- S3.gov verifiedNIH National Library of Medicine, MedlinePlusPanax Ginsengmedlineplus.gov/druginfo/natural/1000.html
- S4.gov verifiedNIH National Library of Medicine, NCBI Bookshelf (LiverTox)Ginsengwww.ncbi.nlm.nih.gov/books/NBK548200/
- S5.gov verifiedNIH National Library of Medicine, NCBI Bookshelf (StatPearls)Ginsengwww.ncbi.nlm.nih.gov/books/NBK538198/
Every figure on this page is quoted from the sources above. Science changes; we re-check and re-date pages as authorities update their guidance.